Difference between DPB and SPB

Two types of pass boxes used in pharmaceutical industries:

1. Dynamic Pass Boxes

2. Static Pass Boxes

A)  The SPB are used to transfer materials between two clean environments which are equally clean and are designed to work with minimum personnel movement while DPB are used to pass materials from an uncontrolled environment to a controlled environment. A SPB should never be used to transfer material between a clean room and a non-clean room.

B)  A DPB is a cubicle box which has  interlocked doors  on both sides. This protects the controlled environment from being polluted while the transfer of a material is taking place inside. A SPB, on the other hand, has got an electromagnetic interlocking which is located between the two doors. The arrangement is fitted with an LED indicator which helps to show whether any door is open.

C)  A DPB has  an Interlock Guard which helps to control both the outlet and the inlet so that there is no time that Both are opened. Due to this, dirt and other air born loose particles are removed from the materials being transferred to the manufacturing area and vice - versa but in case of  SPB, SPB doesn't have such a feature since it only transfers material between two equally clean environments.

D)  DPB is fitted with a suction filter of around 0.3 microns that is a stainless steel product and a supply filter of about 10 microns that is made of aluminium. A SPB doesn't have the filters. The Dynamic Pass Box also has a pressure gauge ranging from 0 to 25 mmwc. It is also fitted with a motor blower of 1/5 hp for blowing out dust particles. The SPB is designed as an air-lock device to prevent ambient air from entering or clean air from disappearing from the clean room.

E)  For a DPB, the UV light's specifications are 18 Watts while that of a Static Pass Box is 8 Watts. The Ultraviolet light with hour mete is controlled by the interlocking arrangement and it goes off when any of the doors open.

F)  The Fluorescent lamp in a SPB is about 40 Watts while that of a Dynamic Pass Box is about 20 Watts. The lamp is controlled by the interlocking and when the doors are closed, the lamp is on.